11/07/2020

A hope for intact memory of immunity in COVID 19 infection

It has been reported that Sars CoV 2 specific IgG/neutralizing antibody decreases in titer in 3 months or less after infection in most cases.

https://www.nature.com/articles/s41564-020-00813-8

This finding makes us suspect of the possible re-infection and of the incompetence of vaccines for long term effectiveness.

The following article in preprint server for COVID 19 related papers shows, however, the humoral as well as the cellular immunity could be maintained in most cases in 6 to 8 months after infection. It is only a preliminary report and won't explain what makes difference in findings from the previous articles. It is of much concern how they have measured the memory function of immunity. It is still giving us a hope for long lasting immunity achieved from the infection as well as from the vaccines now being developed. In most viral infections other than Sars CoV 2 infection, cellular immunity works more than humoral immunity does. If the memory function of cellular immunity works intactly as with the other viruses, as this article says, it is an evangel in the clinical and preventive medicine.  

 https://www.biorxiv.org/content/10.1101/2020.11.06.371617v1

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