Lithium could be a new treatment for Azheimer's disease

There is no decisive blow of treatment for Alzheimer's disease yet. Monoclonal antibodies against beta amyloid have been used in clinical medicine with limited success, that is, only reducing the progress of the disease to an extent. They could cause pretty serious side effects including cerebral bleeding. So no definite choice of treatment yet.

Here is an article in Nature which could sets off  a new horizon for the treatment and/or prevention of Alzheimer's disease. Lithium could be such a medicine as it says from the standpoint of pathophysiological findings in mouse as well as of human pathological data. Lithium carbonate has been a drug for bipolar disorder for a long time. But it has only narrow width of concentration for treatment and could cause serious complication with overdose. Lithium orotate is introduced as a substitute. Lithium won't matter patent and, if lithium is proved clinically effective to prevent and treat Alzheimer's disease with double blind study, the medication of lithium won't cost so expensive as the antibody med or other forms of cutting edge drug. It would be another advantage of lithium med. 

 Aron L, et al. Lithium deficiency and the onset of Alzheimer’s disease. Nature. 2025. https://doi.org/10.1038/s41586-025-09335-x

If lithium med is proved to be of use, hasten to publish it in the market. Millions of people must be waiting for it. John AC4CA should have been one of them since he had his wife Jackie suffering from Alzheimer's disease and was always concerned about any new treatment.